GrandeLASH-MD: When Research and Efficacy Converge

Beauty Professor blogger Rachel Anise Wegter holding GrandeLASH-MD

I’ve been a beauty writer for over 12 years and, while safety in the products I choose to use has always been a crucial focus for me, it’s exciting to see the increase in consumers actively having conversations about ingredients and transparency in the beauty industry. What’s equally refreshing is when a beauty brand goes above and beyond to conduct an array of third-party safety studies not required by law to thoroughly establish performance standards and further validate customer trust. 

GrandeLASH-MD products
On my lashes for over a decade…GrandeLASH-MD.

GrandeLASH-MD: When Research and Efficacy Converge

Such is the case with Grande Cosmetics, which I’ve been using since before I started Beauty Professor. Known internationally for its efficacious lash and brow serums, Grande continues to lead the way in clinical studies, making GrandeLASH-MD one of the most-studied lash serums on the market. However, social media ostensibly has helped contribute to the excessively blurry boundaries between information (proven facts), misinformation (information that is inaccurate or confused) and disinformation (involving a deliberate attempt to mislead) and no brand, however upstanding, is immune from the scrutiny that can stem from trending content. 

Let’s take a closer look at GrandeLASH-MD and how Grande Cosmetics has implemented research to ensure its products are safe and effective both currently and in the long term…

A GrandeLASH-MD ingredients analysis.


With over 60,000 5-star reviews and 10 million units sold, GrandeLASH-MD delivers proven results. 

Cruelty-free and paraben-free, GrandeLASH-MD is powered by performance-based ingredients that actually work. The formula features Isopropyl Cloprostenate – a prostaglandin analogue that helps to enhance the appearance of eyelashes – plus other key players like Radish Root Ferment, Grape Seed Extract, Amino Acids, Hyaluronic Acid, and Honey & Aloe Vera, which all work safely and synergistically together to bring you longer, thicker, and healthier looking lashes in 4-6 weeks. 

Now, when it comes to lash serums, the most well known prescription and cosmetic formulas contain prostaglandin analogues, however, there is a notable difference between each category. Prescription formulas contain a much higher concentration of prostaglandin analogues. Past studies of prescription lash serums have found that prostaglandin analogues at the concentration only seen in prescription lash serums can cause irritation, and although rare, over time can cause iris color change or periorbital fat loss. 

These concerns do not fully translate to cosmetic lash formulas, such as GrandeLASH-MD, with the level of Isopropyl Cloprostenate (a form of a prostaglandin analogue) at a much lower concentration. To dispel some common myths circulating social media and to ensure the safety of GrandeLASH-MD, Grande Cosmetics recently conducted their largest clinical study to date!

The latest GrandeLASH-MD research.


GrandeLASH-MD underwent an extensive 8-month third-party clinical study and toxicological review of its formula and individual ingredients. The clinical study featured 120 participants (this is an exceptionally significant sample size, by the way) who used GrandeLASH-MD as directed and the results proved that the formula is:

-Safe for use as directed

-Does not cause periorbital fat loss 

-It does not cause iris color change

-Does not cause long-term sensitivities 

-Safe for contact lens wearers

-Ophthalmologist tested

In summation, of the 120 individuals in the study, only 2 participants discontinued use due to transient adverse events where symptoms resolved. Additionally Grande Cosmetics has conducted 10 other third-party safety studies—from Toxicological Risk Assessments and RIPT to HET-CAM and In-Use Home Studies and results consistently and conclusively prove that the ingredients in GrandeLASH-MD are safe for intended use.

When a company chooses to engage in an impressive battery of elective research to continually demonstrate product safety, such transparency should be commended and, as an avid GrandeLASH-MD consumer, these studies reinforce the trust I’ve had in the brand since the beginning.

Rachel Anise Wegter the blogger behind Beauty Professor is holding the GrandeLASH-MD
How I use GrandeLASH-MD.


As a contact lens wearer, I am inordinately careful with what I subject my sensitive eyes to and in over a decade of regular use, GrandeLASH-MD has never caused discomfort or irritation. I apply the GrandeLASH-MD to my upper lashes in a single swipe (like a liquid eyeliner) and make sure my brows get a dose of the GrandeBROW before going to bed. 

woman's hand holding GrandeLASH-MD
My GrandeLASH-MD Results.


As aforementioned, I’ve used Grande serums for well over a decade and my lashes and brows have never been better. Every time I am consistent with my routine, my lashes are enhanced and my brows are feathery and thriving. I also love the 2-in-1 Brow Tint (full review HERE) and GrandeBROW-Laminate which take my results to the next level. There are a lot of products on rotation here at BP headquarters but my GrandeLASH-MD and GrandeBROW will continue to be staples as they are a permanent part of my regimen.

grandelash-md review
Last look.

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As a beauty consumer, being informed about the products we use is essential, but in a world where unfounded opinions can spread like wildfire (especially on social media), it is crucial that we form our perspectives based on proven research and third-party clinical studies rather than accepting unsupported allegations as unmitigated truth. 

I hope I’ve helped to shed some light on an oft-discussed topic and, of course, dispelled some myths surrounding the ingredients in GrandeLASH-MD in the process. Use Beautyprofessor15 for 15% off Grande Cosmetics site wide and let me know if you have questions and would like any other suggestions. 

Good things ahead, including an on-location travel beauty look (just like the old days of BP!), some fresh tutorials and a host of new product launches.

In the meanwhile, I post daily content on my Instagram and LTK shop  so please make sure to follow me there, too.

Stay strong, seek wisdom, much love and more soon.


—The Beauty Professor 


**Many thanks to Grande Cosmetics for sponsoring this post. PR samples provided for review denoted by an asterisk (the rest purchased by me). However, as always, all of my opinions are expressly and unequivocally my own. © 2012-2024. Beauty Professor® All Rights Reserved. Do not copy, reprint or republish content and/or photos without author’s written permission.

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